diff --git a/core/modules/content_moderation/content_moderation.module b/core/modules/content_moderation/content_moderation.module
index 921fe2a0c592c2ad75597e047bb7ae50ca524c25..b67fbd3dfc60f6a1573204e020ada4b4418e0b6d 100644
--- a/core/modules/content_moderation/content_moderation.module
+++ b/core/modules/content_moderation/content_moderation.module
@@ -231,6 +231,20 @@ function content_moderation_entity_bundle_info_alter(&$bundles) {
   }
 }
 
+/**
+ * Implements hook_entity_bundle_delete().
+ */
+function content_moderation_entity_bundle_delete($entity_type_id, $bundle_id) {
+  // Remove non-configuration based bundles from content moderation based
+  // workflows when they are removed.
+  foreach (Workflow::loadMultipleByType('content_moderation') as $workflow) {
+    if ($workflow->getTypePlugin()->appliesToEntityTypeAndBundle($entity_type_id, $bundle_id)) {
+      $workflow->getTypePlugin()->removeEntityTypeAndBundle($entity_type_id, $bundle_id);
+      $workflow->save();
+    }
+  }
+}
+
 /**
  * Implements hook_ENTITY_TYPE_insert().
  */
diff --git a/core/modules/content_moderation/tests/src/Kernel/ContentModerationStateTest.php b/core/modules/content_moderation/tests/src/Kernel/ContentModerationStateTest.php
index 5fe22adb8eb379b9ad9f0c12acce8325311ae16d..55173dd270440c1cf67c6f5759903c2cf306ee9b 100644
--- a/core/modules/content_moderation/tests/src/Kernel/ContentModerationStateTest.php
+++ b/core/modules/content_moderation/tests/src/Kernel/ContentModerationStateTest.php
@@ -461,6 +461,41 @@ public function testWorkflowDependencies() {
     $this->assertEquals([], $entity_types);
   }
 
+  /**
+   * Test the content moderation workflow dependencies for non-config bundles.
+   */
+  public function testWorkflowNonConfigBundleDependencies() {
+    // Create a bundle not based on any particular configuration.
+    entity_test_create_bundle('test_bundle');
+
+    $workflow = Workflow::load('editorial');
+    $workflow->getTypePlugin()->addEntityTypeAndBundle('entity_test', 'test_bundle');
+    $workflow->save();
+
+    // Ensure the bundle is correctly added to the workflow.
+    $this->assertEquals([
+      'module' => [
+        'content_moderation',
+        'entity_test',
+      ],
+    ], $workflow->getDependencies());
+    $this->assertEquals([
+      'test_bundle',
+    ], $workflow->getTypePlugin()->getBundlesForEntityType('entity_test'));
+
+    // Delete the test bundle to ensure the workflow entity responds
+    // appropriately.
+    entity_test_delete_bundle('test_bundle');
+
+    $workflow = Workflow::load('editorial');
+    $this->assertEquals([], $workflow->getTypePlugin()->getBundlesForEntityType('entity_test'));
+    $this->assertEquals([
+      'module' => [
+        'content_moderation',
+      ],
+    ], $workflow->getDependencies());
+  }
+
   /**
    * Reloads the entity after clearing the static cache.
    *